Summary:
How do I populate PerfectMail with my list of e-mail addresses or users? Is there some way for this information to get populated automatically using Active Directory or some other means?

PerfectMail has auto-discover functionality to learn your organizations e-mail addresses. This reduces the work load on the mail admin in having to maintain user lists in multiple places.

PerfectMail uses discovered users to record e-mail traffic statistics to build relationships between e-mail peers, to aid with anti-spam decisions.

The PerfectMail server builds up a list of users by watching e-mail traffic. PerfectMail can be configured to query your mail server using SMTP Recipient Filtering for e-mail address validation. To reduce the volume of new address requests from data miners a filter may delay first time sender/recipient combinations. (You can turn this off in Filtering=>Filter Settings by disabling Delay new address queries under General Filter Options.)

Addresses are removed from the list of Discovered Users, when the e-mail activity for an address drops to zero over an extended period of time and your mail server no longer reports the address as being valid.